4 ms·
I was a bit confused until I noticed that this is only a partial sequence. A full antibody is considerably larger, and you also need to get the disulfide bonds
by fabian2k 9y ago
I was a bit confused until I noticed that this is only a partial sequence. A full antibody is considerably larger, and you also need to get the disulfide bonds formed correctly for it to work.
And I don't think it is entirely clear if expressing that antibody alone is enough to defeat HIV, especially as it targets the immune system itself. If antibodies are the solution, then developing a vaccine that triggers the production of suitable antibodies is probably the better way forward.
- toufka 9y agoYep. It's just the heavy chain. If it's expressed in vivo (in the right place) it should form properly. And N6 isn't a full cure, but it has shown therapeutic benefit. Details do matter, but the general idea still stands. The vaccines that trigger antibody production actually are being made.