3 ms·
From the paper, it sounds like the particle they constructed is about 120nm in diameter. So a bit larger than the viruses previously used. Which are also nanopa
by lukeschlather 9y ago
From the paper, it sounds like the particle they constructed is about 120nm in diameter. So a bit larger than the viruses previously used. Which are also nanoparticles, so I guess it's more that this delivery system isn't based on a virus.
I guess, one thing I don't quite understand: are the viruses used in CRISPR really viruses (can they self-replicate using the cells they alter?) Or are they just nanomachines based on viruses?
- 88e282102ae2e5b 9y agoThe viruses used to deliver CRISPR in the past are not able to replicate. They're so small that you have to remove all of the viral DNA in order to even fit your CRISPR-coding genes inside.
- Parcissons 9y agoWhy is the whole virus needed? Not just the docking mechanism?