It really depends on what you already know and your level of interest in learning something new. I can still crank out a pretty neat Web App in Code Igniter ov

It really depends on what you already know and your level of interest in learning something new. I can still crank out a pretty neat Web App in Code Igniter over lunch! But, nowadays, I use Meteor which makes things very efficient while making an old hag look cool too :-) (Meteor allows you to leverage the great work available in the node community quite seamlessly)