3 ms·
This is exactly how science works. They report this possible case. Maybe there is never another association and the issue is forgotten, because there is no cau
by joshgel 9y ago
This is exactly how science works.
They report this possible case. Maybe there is never another association and the issue is forgotten, because there is no causal link. But maybe, someone else, some place else, who never read this paper, notices something similar and reports it. And maybe this happens several more times. And then, along the way, one of these reporters does a detailed search and finds the other reports. He collects the cases and maybe contacts the doctors who wrote the reports and writes what we call a Case-Series on these.
Maybe a couple case-series get written independently in various places. Someone finds these series and convinces someone else to fund a Case Control study.
Usually with environmental exposure literature this is exactly how "science" happens. Medicine is messy and serendipity is more than involved.
Hierarchy of evidence:
http://ebm.bmj.com/content/early/2016/06/23/ebmed-2016-110401 http://ebm.bmj.com/content/early/2016/06/23/ebmed-2016-11040...