3 ms·
A simple hypothesis which could explain this might be that the plaques cause effectivelt permanent brain damage. The question is whether degenerative patterns c
by eganist 9y ago
A simple hypothesis which could explain this might be that the plaques cause effectivelt permanent brain damage. The question is whether degenerative patterns ceased or slowed after substantial clearing of plaques from the brain.
I would expect this test (and therefore the hypothesis) to fail if the plaques themselves are a byproduct rather than the cause of degradation in brain function. That said, I'm surprised I haven't read much in Gates' Notes or other funding sources on potential ties to HSV1 considering all the increasingly supportive research between the two.
- JamesBarney 9y agoThey used several techniques that clear beta amyloid from the brain.(antibodies and ultrasound). And they've have little if any effect on cognition. I'm starting to think beta amyloid is a red herring, or maybe just important in the prodromal stages of the disease.
- reasonattlm 9y agoAnother point is that a majority of Alzheimer's patients have other neurodegenerative conditions, with vascular dementia being one of the most common. So it is reasonable to expect that you can in fact meaningfully address Alzheimer's and see little to no improvement in a patient.