OTC standard dose for regular strength Tylenol is 1-2 capsules x 325mg. They are giving the patients 1000mg or the equivalent of two extra strength pills (500mg

OTC standard dose for regular strength Tylenol is 1-2 capsules x 325mg. They are giving the patients 1000mg or the equivalent of two extra strength pills (500mg). While both are 'standard' doses, I think the poster's point is that they're comparing 'regular strength' opiates (5mg of oxy/hydrocodone) with extra strength acetaminophen (1000mg acetaminophen). If they wanted a proper comparison, they should compare 7.5 or 10mg of oxy/hydrocodone with 1000mg of acetaminophen. Also, because the oxy/hydrocodone pills they test also contain acetaminophen you'd think they'd test the efficacy of oxy/hydrocodone by themselves as well, but apparently that didn't cross their minds. It definitely looks to me like the combinations tested were chosen so as to get a predetermined result.