3 ms·

last I heard the results looked excellent under a microscope Do you have a reference to some images I could look at?

by davi 16y ago

Eliezer 16y ago
Fired off your question to Aschwin de Wolf and got back: http://www.alcor.org/Library/html/newtechnology.html http://www.alcor.org/Library/html/newtechnology.html (Figure 4 and 5 for the more recent technology, earlier photos are older technology) http://www.alcor.org/Library/html/braincryopreservation1.html http://www.alcor.org/Library/html/braincryopreservation1.htm... (photos as of 1995 tech) Aschwin also notes this paper is important: http://www.ijcep.com/707005A.html http://www.ijcep.com/707005A.html
- davi 16y ago
  Thanks for inquiring and relaying the response you got. Here is an example of the scale I'm interested in: http://synapses.clm.utexas.edu/atlas/1_6_2.stm http://synapses.clm.utexas.edu/atlas/1_6_2.stm Things that look like the newtechnology.html's figs 4 & 5 can look very bad at higher mags. I know this from painful experience. I don't see any high mag pictures at newtechnology.html or in Lemler et al. 2004, which that page cites. These mags are quite accessible once one has gone to the trouble of preparing sections for transmission electron microscopy. Sheleg et al. 2008 was interesting and surprising to me. It is published in a journal not included in the ISI Science Citation Index, so I can't tell at a glance how their paper might have been received by other workers. I might try replicating their results myself at some point down the road, it would be a pretty simple experiment for me to do (at least, the EM part, not the histology work). I understand the hope that even anatomically degraded tissue could retain sufficient information for cryonics to be useful. I just don't plan to bet my own money on this hope, at least not at this time.
  - Eliezer 16y ago
    Aschwin says it's a reasonable request and he knows they've got those and he'll see if he can make them available. I'll reply again when/if the info is available. Any particular way in which I should contact you, if this conversation goes stale?
    - davi 16y ago
      Yes, I'd be interested in seeing higher mag pictures if they become available. An email to <any address>@<the domain in my HN profile> will reach me.

last I heard the results looked excellent under a microscope Do you have a reference to some images I could look at?

by davi 16y ago

last I heard the results looked excellent under a microscope Do you have a reference to some images I could look at?

Fired off your question to Aschwin de Wolf and got back: http://www.alcor.org/Library/html/newtechnology.html http://www.alcor.org/Library/html/newtechnology.html (Figure 4 and 5 for the more recent technology, earlier photos are older technology) http://www.alcor.org/Library/html/braincryopreservation1.html http://www.alcor.org/Library/html/braincryopreservation1.htm... (photos as of 1995 tech) Aschwin also notes this paper is important: http://www.ijcep.com/707005A.html http://www.ijcep.com/707005A.html

davi 16y ago
Thanks for inquiring and relaying the response you got. Here is an example of the scale I'm interested in: http://synapses.clm.utexas.edu/atlas/1_6_2.stm http://synapses.clm.utexas.edu/atlas/1_6_2.stm Things that look like the newtechnology.html's figs 4 & 5 can look very bad at higher mags. I know this from painful experience. I don't see any high mag pictures at newtechnology.html or in Lemler et al. 2004, which that page cites. These mags are quite accessible once one has gone to the trouble of preparing sections for transmission electron microscopy. Sheleg et al. 2008 was interesting and surprising to me. It is published in a journal not included in the ISI Science Citation Index, so I can't tell at a glance how their paper might have been received by other workers. I might try replicating their results myself at some point down the road, it would be a pretty simple experiment for me to do (at least, the EM part, not the histology work). I understand the hope that even anatomically degraded tissue could retain sufficient information for cryonics to be useful. I just don't plan to bet my own money on this hope, at least not at this time.
- Eliezer 16y ago
  Aschwin says it's a reasonable request and he knows they've got those and he'll see if he can make them available. I'll reply again when/if the info is available. Any particular way in which I should contact you, if this conversation goes stale?
  - davi 16y ago
    Yes, I'd be interested in seeing higher mag pictures if they become available. An email to <any address>@<the domain in my HN profile> will reach me.