I still lean on item 1 being the most correct. I know modern society is built on a "do anything" approach but in reality we're under the gun of biology and evol

I still lean on item 1 being the most correct. I know modern society is built on a "do anything" approach but in reality we're under the gun of biology and evolution and as such only certain behavioral patterns are actually successful. I found losing weight and staying fit got a lot easier when I focused on discipline instead of quick fixes like Atkins. There's an art to pushing back on that neurological trigger craving that dopamine shot and it can be learned. (Of course, if a pill comes out to help you with that trigger, then we're golden). Or more practically, a way to produce leptin and ghrelin in the body so hunger and craving response goes way down. I'm not saying I'm "against" the pill, but no pill is going to magically erase 1,000+ calories of over-eating or clear out all the awful things excess sugar and other carbs may do. It may certainly mitigate them, but like the person I know who got lapband surgery eventually found out, his eating just adapted to his new limitations (ice cream, sweets, etc dont take much room and are very high energy) and he gained weight after a while. We'll pop the pill, eat like pigs, and be at the same weight or higher after a while. I imagine if this becomes a mass market medicine, its effective applications will be outside of weight control and more towards helping people achieve a certain level of fitness especially those with limited mobility or illness. Its not something you're going to buy able to buy over the counter for 'free' workouts. The same way you can't buy testosterone or steroids OTC.