There is a brief section dedicated to this: https://www.wireguard.com/quickstart/#nat-and-firewall-traversal-persistence https://www.wireguard.com/quickstart/#n

There is a brief section dedicated to this: https://www.wireguard.com/quickstart/#nat-and-firewall-traversal-persistence https://www.wireguard.com/quickstart/#nat-and-firewall-trave... tl;dr keepalives and the expectation of a statefull firewall keeping things open. Combined with touting IP roaming as a feature, I think it is something wireguard cares about.