Dying of an overdose or doing well at the expense of others are things that most people can agree are things we ought not to want. But I haven't found a reason

Dying of an overdose or doing well at the expense of others are things that most people can agree are things we ought not to want. But I haven't found a reason that I ought not to want those, ultimately. It just so happens that I (and most people) don't. Whenever you see yourself saying, "you ought to"/"it's good to"/"it's moral to", notice the immediate reason that the statement seems true (assuming it does) is to satisfy some goal. You have a goal of not hurting other people (or, to say it another way, you want not to hurt other people), but while that suffices for directing your thoughts and actions on this level, if you back up a level, you'll see that this goal is in service of another goal. If human goal systems were regular and consistent, there would ultimately be a topmost goal which all this was pointing at. But that doesn't seem to be the case, so we're left shifting about aimlessly, considering only that which we happen to consider (our happiness, the happiness of others, life satisfaction, or whatever) without anything to direct what we ought to be doing. Making up your own meaning doesn't solve this problem, but only ignores it. It might be that it's unsolvable (I currently think so, at least), but in that case, it can hardly matter that one keeps looking.