Ah, but interestingly, inhibiting either cox pathway independently doesn't damage mucosa. you have to inhibit both, simultaneously, and the limiting factor is t

Ah, but interestingly, inhibiting either cox pathway independently doesn't damage mucosa. you have to inhibit both, simultaneously, and the limiting factor is the one that is the least inhibited. So it's not just "COX-2 good, COX-1 bad", it's actually "Either pathway is fine to inhibit selectively as long as you don't inhibit both"