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I'm wondering what other HN users think of the merits of reducing the omega-6 to omega-3 ratio as an alternative to aspirin (in certain cases). Aspirin works b

I'm wondering what other HN users think of the merits of reducing the omega-6 to omega-3 ratio as an alternative to aspirin (in certain cases). Aspirin works by irreversibly inactivating the COX enzyme [0], which is involved the Arachidonic Acid Cascade [1], which at the same time is affected by the aforementioned essential fatty acid ratio. COX enzyme inactivation supresses the production of thromboxanes, which explains your bleeding. [0] https://en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin https://en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin [1] https://en.wikipedia.org/wiki/Essential_fatty_acid_interactions https://en.wikipedia.org/wiki/Essential_fatty_acid_interacti... Edit: Added last parragraph

teslabox 9y ago
I think it's better to reduce total PUFA consumption, than to dilute out omega-6's with omega-3's. Both types of oils are unstable at body temperature. Human operating temperature is much closer to a cow (or coconut) than to an artic fish.
- stayingwithher 9y ago
  Is that you Peat?
- miguelrochefort 9y ago
  http://raypeat.com/articles/articles/unsaturatedfats.shtml http://raypeat.com/articles/articles/unsaturatedfats.shtml
- driverdan 9y ago
  > Human operating temperature is much closer to a cow (or coconut) than to an artic fish. Why is that relevant?
  - drharby 9y ago
    Im infering that the chemistry of said oils vary enough between the two temps to matter Its the implication
debacle 9y ago
Great links. Thanks.