3 ms·
Some papers showing direct connections between senescent cells and specific aspects of aging, in many cases turning back that aspect by removing the senescent c
by reasonattlm 9y ago
Some papers showing direct connections between senescent cells and specific aspects of aging, in many cases turning back that aspect by removing the senescent cells.
Osteoporosis: https://doi.org/10.1038/nm.4385 https://doi.org/10.1038/nm.4385
Fatty liver disease: https://doi.org/10.1038/ncomms15691 https://doi.org/10.1038/ncomms15691
Disruption of platelet formation: https://doi.org/10.3389/fonc.2017.00188 https://doi.org/10.3389/fonc.2017.00188
Osteoarthritis: https://dx.doi.org/10.1038/nm.4324 https://dx.doi.org/10.1038/nm.4324
Disruption of regeneration: https://doi.org/10.3389/fcell.2017.00049 https://doi.org/10.3389/fcell.2017.00049
Lung fibrosis: https://doi.org/10.1183/13993003.02367-2016 https://doi.org/10.1183/13993003.02367-2016
Pulmonary function in general, including tissue elasticity: https://doi.org/10.1172/jci.insight.87732 https://doi.org/10.1172/jci.insight.87732
Atherosclerosis: http://dx.doi.org/10.1126/science.aaf6659 http://dx.doi.org/10.1126/science.aaf6659
Vascular calcification: http://dx.doi.org/10.18632/aging.101191 http://dx.doi.org/10.18632/aging.101191
Chronic kidney disease: https://doi.org/10.18632/oncotarget.17327 https://doi.org/10.18632/oncotarget.17327
Cardiac hypertrophy: https://doi.org/10.1371/journal.pone.0182668 https://doi.org/10.1371/journal.pone.0182668
Cardiac fibrosis and function in general: https://doi.org/10.1093/eurheartj/ehx454 https://doi.org/10.1093/eurheartj/ehx454