Work in this area is interesting but to me seems like pharma money as the focus is on messing with things that suck money for a long time and then end in cancer

Work in this area is interesting but to me seems like pharma money as the focus is on messing with things that suck money for a long time and then end in cancer. Or put another way what happens to the carbs that are blocked from getting processed. Knowing which cell types are the most resistant to this intervention may have lots of value, but a new block buster drug would be a crime. So suck it up and learn to truly get into a ketogenic state then see where in the world you are. There is little research on multiyear ketogenic cohorts. Fasting which has many comparators to ketosis has been in most cultures for years. A general theme here is insulin sensitivity or better put lack there of. I do not see how this pathway disrupting mechanism helps to return insulin sensitivity for a person eating the diets recommended by pretty much all governments globally.