2 ms·
Thanks, actually the wikipedia link was "per generation" and they assume ~ 100 divisions/mitoses per human generation. So it should be 1e-10 mutations/bp/divisi
by nonbel 9y ago
Thanks, actually the wikipedia link was "per generation" and they assume ~ 100 divisions/mitoses per human generation. So it should be 1e-10 mutations/bp/division.
However, that is for germline, somatic mutation rates are apparently 10-100x more more common: https://www.nature.com/articles/ncomms15183 https://www.nature.com/articles/ncomms15183
These rates no doubt vary by cell type, environment, etc. I was actually thinking something like 1e-6 to 1e-10 mutations/bp/division.