> “The problem is, when you have the same exact words, it’s hard to assemble,” said Lander, just as if jigsaw puzzle pieces show the same exact blue sky. This

> “The problem is, when you have the same exact words, it’s hard to assemble,” said Lander, just as if jigsaw puzzle pieces show the same exact blue sky. This is inaccurate, though the fault is with the author, not Lander. When you have genomic repeats, the appropriate analogy is if you had multiple puzzle pieces that had the exact same edges on all sides. Puzzle pieces that show the same blue sky but with different edges can still be uniquely assembled. But puzzle pieces with identical edges create non-unique but equally satisfactory assembly solutions, and this is the case with the problem of genomic assembly.