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Just wanna say that my wife has a PhD in nutrition and this isn't news to us. We've "known" that unbound fructose is hard on the liver for years.
by teach 9y ago
Just wanna say that my wife has a PhD in nutrition and this isn't news to us.
We've "known" that unbound fructose is hard on the liver for years.
- ShabbosGoy 9y agoWhat isn't hard on your liver these days? Most drugs undergo metabolism and activation through the CYP450 system. Meaning that those drugs which clear hepatically are most likely hard on your liver in the long run.
- Sevrene 9y agoModeration is the important thing here. It's easier to avoid consuming drugs every day compared to eating a high fructose diet.
- coderdude 9y agoDepends on who you're using as an example. If you're consuming too much alcohol or other, obvious well-known substances that cause liver damage it might be easier to eat healthy than it would be to not consume. (From a mental/logical standpoint.) Point is, the onslaught on the liver is coming from all angles. Actual kids are being hurt unknowingly in a similar way that "college kids" are being knowingly hurt. Moderation shmoderation. Choice isn't always a factor for those affected.
- nate_meurer 9y agoJust because a CYP is involved, doesn't mean the target substance is hard on your liver in any way. Liver toxicity is highly non-linear with dosage, and damage typically starts abruptly when substrates are depleted. The classic example is paracetamol, which is quite safe at reasonable dosages (and without alcohol) where the liver is well within its limits, but causes damage rapidly at higher dosages when you run out of glutathione.
- Godel_unicode 9y agoThis nuanced explanation is sadly lacking in many places I encounter the phrase "liver damage". I have frequently read articles which would lead one to believe that things are bad for your liver linearly and are "unsafe at any speed". It's irritating.
- sbenitoj 9y agoYour wife is one of the few pedigreed nutrionists who “knows” that! Sadly most nutritionists are overweight themselves and continue to advocate people consume whole grains, low-fat dairy, and fruit to lose weight/be healthier. Kudos to your wife for ignoring the massive amount of BS most doctors and nutritionists are inculcated with!
- teach 9y agoThere's nothing wrong with whole grains or fruit. The book "Wheat Belly" is terrible science. Also, my wife is a registered dietitian with a PhD, not a "nutritionist".
- equippan 9y agoWhat is wrong with whole grains or fruit? I have never heard of that before.
- why-el 9y agoNothing, I think the parent is wrong or misspoke. The advice is usually "substitute bad processed sugar with fruit", which is what Dr Lustig has advocated for the last decade. Of course too much fruit is itself bad, since the fiber can only do so much.
- taysic 9y agoWhy would too much fruit be bad? This is sadly a myth that gets formed when “sugar is bad” is oversimplified.
- brianwawok 9y agoA balanced diet is important. Fruit only covers certain parts. And yes it also has a bit much sugar. Replace 80% of your fruit with veggies and you will be better off.
- didibus 9y ago
- rjeli 9y agowhat do you and your wife eat?
- nikkwong 9y agoMy guess would be nuts, vegetables, and meats (like fish). Some fruits are okay though, like low sugar ones (avocados). I personally have tested my diet for years and found this diet to be optimal for me, and in line with most current research on what the body needs—and what the body should stay away from. Many people would consider a diet like this difficult, but if you approach it correctly (I end up cooking a lot of szechuan cuisine), it's quite easy—and delicious!
- wickawic 9y agoWhile insightful, you very strangely answered a personal question directed at another user. How could you know what they eat?
- teach 9y agoEverything except red meat and dairy, honestly. But if you want to know what we believe to be true about which foods are healthy, there's probably no better starting point than Harvard's Healthy Eating Plate. - https://www.hsph.harvard.edu/nutritionsource/healthy-eating-plate/ https://www.hsph.harvard.edu/nutritionsource/healthy-eating-...
- dbcurtis 9y agoso, not paleo. Does your wife have comments on the paleo diet thesis?
- teach 9y agoMy bumper-sticker answer is basically that paleo proposes some of the right things but for the wrong reasons. Avoiding processed foods and refined sugar is good. Avoiding dairy is good. But there's no reason in general to avoid cereal grains, legumes or potatoes unless you're sensitive/allergic. And higher-quality meat is an improvement over the status quo but a vegetarian diet is likely to be healthier. But all that is me talking, not my wife. I suspect she would say similar things but honestly we don't spend a lot of time discussing the random fad diet book du-jour.
- wutbrodo 9y agoYea, as uncertain as a lot of nutritional science can be, and as ill informed as even otherwise well informed people can be about it: "too much fructose can damage your liver" is not something I thought was remotely controversial or novel.
- vram22 9y agoWhat is unbound fructose, and can you give some links about it?
- hasenj 9y agoI think he means fructose that is not bound to glucose ..
- CodeWriter23 9y ago> Just wanna say that my wife has a PhD in nutrition and this isn't news to us. Does she recommend low fat food alternatives to her patients? My nutritionist pushed them like the gospel. And she would tell us in the next sentence that most low fat foods had added sugar to increase the flavor.