3 ms·
Protein staining in the study of Alzheimer’s disease is a common (and old) element of its analysis. This is part of how we identified tau protein plaque formati
by arkades 9y ago
Protein staining in the study of Alzheimer’s disease is a common (and old) element of its analysis. This is part of how we identified tau protein plaque formation as part of the disease.
Prions are not part of the disease. They would stain, and be visible on microscopy. They are exactly the (type of) substance that has been stained for, and are more than large enough to show up on the various types of microscopy regularly performed on these tissue samples.
I’m trying to find a more explicit way of saying: these are easy to eee in exactly the ways that we examine these brains, so no, it’s not a prion disease.
- eth0up 9y agoAny insight on the possibility of transmissible amyloid pathology? http://www.nature.com/news/the-red-hot-debate-about-transmissible-alzheimer-s-1.19554 http://www.nature.com/news/the-red-hot-debate-about-transmis...
- dnautics 9y agoIt's super unlikely. Having worked in the field, I am almost certain that amyloids are a consequence of, not a cause of the disease. Otherwise, valeant's drug would not have failed so spectacularly a few weeks ago.