4 ms·

Actually, not even "have to" do that. That makes it seem like the people coming up with these treatments should be an adversary to patients. Shouldn't they wan

by nonbel 9y ago

Actually, not even "have to" do that. That makes it seem like the people coming up with these treatments should be an adversary to patients. Shouldn't they want to share as much info as possible? That would seem necessary to convince possible patients (and/or any advisers) that this will help them.

refurb 9y ago
Kite is a start-up in a very competitive field. It wouldn't surprise me that publishing data wasn't that high of a priority vs. getting FDA approval. That said, it's very common for biotechs to publish after the phase 3 is complete as they can put much more information in the paper vs. what their sales reps can say to physicians.
- nonbel 9y ago
  >"It wouldn't surprise me that publishing data wasn't that high of a priority vs. getting FDA approval." I see, so the problem is physicians/patients are willing to act on very sparse information, so why bother providing it.
  - refurb 9y ago
    You clearly don't understand the pace of work at a biotech start-up. If you could only do one or the other, which would you choose? 1. All hands on deck to get the FDA submission completed so the drug can get to patients sooner. 2. Peel off a bunch of headcount to get a handful of papers published, knowing that will result in a delay in getting the drug to patients?
    - nonbel 9y ago
      When patients/doctors are willing to put all their eggs in one basket (FDA approval), this seems like a perfectly reasonable business plan. However, for the best chance to find out if your drug really is working the way you think it does, you will need actual public examination of the results. You'll want to see what critiques people come up with, make some predictions about future results, whether an independent group can replicate your work, etc. Although it is nowhere near a guarantee, sharing your results/methods is another of those heuristics (like do independent replications, and make precise predictions about future observations) that served as the basis of science for so long. More and more I see science being replaced by "something else". This something else is definitely a faster process...

by nonbel 9y ago

refurb 9y ago

Kite is a start-up in a very competitive field. It wouldn't surprise me that publishing data wasn't that high of a priority vs. getting FDA approval. That said, it's very common for biotechs to publish after the phase 3 is complete as they can put much more information in the paper vs. what their sales reps can say to physicians.

nonbel 9y ago
>"It wouldn't surprise me that publishing data wasn't that high of a priority vs. getting FDA approval." I see, so the problem is physicians/patients are willing to act on very sparse information, so why bother providing it.
- refurb 9y ago
  You clearly don't understand the pace of work at a biotech start-up. If you could only do one or the other, which would you choose? 1. All hands on deck to get the FDA submission completed so the drug can get to patients sooner. 2. Peel off a bunch of headcount to get a handful of papers published, knowing that will result in a delay in getting the drug to patients?
  - nonbel 9y ago
    When patients/doctors are willing to put all their eggs in one basket (FDA approval), this seems like a perfectly reasonable business plan. However, for the best chance to find out if your drug really is working the way you think it does, you will need actual public examination of the results. You'll want to see what critiques people come up with, make some predictions about future results, whether an independent group can replicate your work, etc. Although it is nowhere near a guarantee, sharing your results/methods is another of those heuristics (like do independent replications, and make precise predictions about future observations) that served as the basis of science for so long. More and more I see science being replaced by "something else". This something else is definitely a faster process...