CPython doesn't really have a "stream mode" like `perl -pi`, but you could easily make a pretty trivial wrapper to do it if you found yourself wanting to duplic

CPython doesn't really have a "stream mode" like `perl -pi`, but you could easily make a pretty trivial wrapper to do it if you found yourself wanting to duplicate that functionality. I'd much rather use sed or awk in your specific case and similar, but to each his own.