Some of the meta data is only kept in ram and updated from time to time to special regions. These special regions can also suffer from endurance issues but are

Some of the meta data is only kept in ram and updated from time to time to special regions. These special regions can also suffer from endurance issues but are usually are SLC-use-MLC so they wear slower but it is a known failure mode for the metadata locations to wear and we've had it happen to us during testing, especially if we did lots of firmware upgrade/downgrade testing.