I've confronted it plenty of times, and for my use cases it's not really an issue. Many numpy functions release the GIL, so by keeping my performance-critical s

I've confronted it plenty of times, and for my use cases it's not really an issue. Many numpy functions release the GIL, so by keeping my performance-critical stuff in numpy it's just not an issue for me. I sometimes split tasks up with multiprocessing, which is a GIL workaround to be sure, but the memory footprint of extra interpreters is negligible compared to the data I work with.