I don't quite understand what you are trying to convey. If you send 100 packets with 10 bytes payload(or TCP segments if you will), I hope it is obvious that th

I don't quite understand what you are trying to convey. If you send 100 packets with 10 bytes payload(or TCP segments if you will), I hope it is obvious that there are more overhead (Ethernet/IP/TCP header of 100 packets) compared to sending 1 packet with a 1000 byte payload. Normally this matters as it is desirable for systems to use less resources, not more. (e.g. we'd want to lessen the load on the network, we'd want applications to have low latency)