Mostly it wouldn't matter. This would basically reflect the preference of SPA vs non-SPA sites or Desktop vs Web app. In both cases the trade-off is similar. A

Mostly it wouldn't matter. This would basically reflect the preference of SPA vs non-SPA sites or Desktop vs Web app. In both cases the trade-off is similar. A big one time download vs small added delays in each request (ignoring the network dependency in each). Of course this preference comes at the bottom of the priority list.