I for one prefer to not have my pipes freeze solid and burst, so I heat my house to a minimum of 60 all the time, and the "unheated" basement (which has no vent

I for one prefer to not have my pipes freeze solid and burst, so I heat my house to a minimum of 60 all the time, and the "unheated" basement (which has no vents from the furnace, merely the furnace itself and radiant heat from the ductwork) keeps at about 50, safely far from freezing.