In pharmaceutical companies much of the stuff that used to be done in-house (synthesis, early discovery &c) is now contracted out to contract research organizat

In pharmaceutical companies much of the stuff that used to be done in-house (synthesis, early discovery &c) is now contracted out to contract research organizations, often overseas. The knowledge-broker model has become more common, work that used to be done by staff scientists is now done by students and postdocs, the risk has been shifted from the company to the employees, and that really has made labour conditions worse.