I never had any trouble getting clisp running under OS X. MacPorts is nice as long as the port you're after actually works. Although, now that I think about i

I never had any trouble getting clisp running under OS X. MacPorts is nice as long as the port you're after actually works. Although, now that I think about it, I do recall the clisp port being broken at some point. I just downloaded the tarball and ./configure;./build'ed it myself, though. PLT Scheme is much easier, though. I'd highly recommend it for any variety of noob. I've installed it with no issues on OS X, Windows, and FreeBSD.