1) Removing inactive subscribers is a good thing. You stop bothering those who've stopped caring (but haven't bothered to unsubscribe) and pay less for your CRM

1) Removing inactive subscribers is a good thing. You stop bothering those who've stopped caring (but haven't bothered to unsubscribe) and pay less for your CRM/email software (if it charges by number of contacts). 2) Marketers should not rely on opens alone to determine who is inactive. Also look at clicks, and site activity from the past 6 months.