3 ms·
Maybe gut bacteria are quite a bit different from bacteria elsewhere in the body, but I had an experience that makes me wonder about antibiotic effectiveness in
by joveian 9y ago
Maybe gut bacteria are quite a bit different from bacteria elsewhere in the body, but I had an experience that makes me wonder about antibiotic effectiveness in general. My sister gave me a couple of ubiome gut bacteria kits and I took one a few weeks before my first course of antibiotics (that I can recall - possibly I had to take them at some point decades ago) and one after two weeks on Amoxicillin/clavulanic acid, which was sampled right at the point where I would have taken the next pill if I wasn't stopping.
In the "microbiome diversity" score, I was at 7th percentile before the antibiotics and 15th percentile after (inverse Simpson's Diversity Index normalized to 10 score went from 6.05 to 6.69). I did a couple of times notice ubiome presenting obviously incorrect information (and they never made a substantial response to reporting the first one) so one possible explanation that I could believe is that ubiome simply presents incorrect data. Another is that gut motility changes and/or somehow due to the diarrhea I got earlier in the treatment there was a larger collection of dead bacteria from meals in my gut the second time. I guess a third is that when alive some bacteria are not only killing others that arrive from meals but destroying them beyond recognition. Still, this makes me wonder a tiny bit if even two weeks of antibiotics doesn't fully kill non-antibiotic resistant bacteria in the gut. I was taking the antibiotics to try to calm down overactive gut bacteria (it helped for a few months), so even if this is the case for me it might not be generally true, but if it is true for anyone than we could be the ones breeding antibiotic resistant bacteria in our gut.