The interoperability is entirely connected to the choices a programming language makes in order to execute a program. A programming language that has a GC will

The interoperability is entirely connected to the choices a programming language makes in order to execute a program. A programming language that has a GC will immediately have somewhat of a challenge in calling native C code. And then there's the identifier problem. Some languages allow different characters than others in identifiers. There are so many issues that interoperability is literally impossible to solve generally or by any single individual.