> So... when you say buprenorphine works great in terms of binding, I get the impression that you mean that the effect lasts longer, and that it is needed less

> So... when you say buprenorphine works great in terms of binding, I get the impression that you mean that the effect lasts longer, and that it is needed less frequently? That would have helpful practical ramifications, yeah. Exactly, yeah. For most people it will "hold" them for 24-48 hours. Unfortunately for me, it only holds me for about 12, but that should hopefully mean that my final withdrawal symptoms are more acute and less drawn out. I'd rather a week or two of agony than months of less-intense but still terrible shit!