This paper (2008) describes the general approach, including the use of Betti numbers for classification of observed phenomena (in primates, not in silico): htt

This paper (2008) describes the general approach, including the use of Betti numbers for classification of observed phenomena (in primates, not in silico): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924880/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924880/