It doesn't matter much, it's all just sugar over virtualenvs (which are quite simple conceptually). Virtualenvwrapper has been around a long time and works pret

It doesn't matter much, it's all just sugar over virtualenvs (which are quite simple conceptually). Virtualenvwrapper has been around a long time and works pretty well. More recent tools are Pipenv (which I've been using) and hatch - I don't think there is any One True Way since the days of virtualenvwrapper being the latest and shiniest. If you want a really easy to use tool that doesn't require any understanding of virtualenvs, I'd look at Pipenv. http://docs.pipenv.org/en/latest/ http://docs.pipenv.org/en/latest/