I've had so many ergo problems. Here's some things I'd suggest: 1. Try different mice, as people suggested 2. Watch the height of your desk. Is your desk to

I've had so many ergo problems. Here's some things I'd suggest: 1. Try different mice, as people suggested 2. Watch the height of your desk. Is your desk too high? Is your wrist kinked? I love my sit stand desk for this, sometimes just moving the surface up or down half an inch makes a huge difference. Keep it moving over time so you don't get locked in. 3. Wrist exercises, both stretching and grip strength. Get a pair of grippers from amazon (https://www.amazon.com/Captains-Crush-Hand-Gripper-Point/dp/B006G377UQ/ref=sr_1_8?s=sports-and-fitness&ie=UTF8&qid=1504724656&sr=1-8&keywords=grip+strength+trainer https://www.amazon.com/Captains-Crush-Hand-Gripper-Point/dp/...) Working on strengthening your forearm might help as well.