On reliability, I've got a much smaller 32GB Samsung EVO microSDXC in an adapter in an Intel NUC formatted Btrfs being used as rootfs for Fedora Server, for 6 m

On reliability, I've got a much smaller 32GB Samsung EVO microSDXC in an adapter in an Intel NUC formatted Btrfs being used as rootfs for Fedora Server, for 6 months with zero errors of any kind including regular scrubbing. I think the latest iterations of these cards (at least brand name anyway) are a lot more reliable than SD cards of yore. Those were meant pretty much strictly as a FAT32/exFAT camera card that you only write to, read off all files from, then reformat to reuse; and were not really meant as a random access device, organizing files, deleting individual files, modifying them, like what an OS would do. I do highly recommend running f3 tests on whatever you buy, f3write followed by f3read, to check for fake flash. There's a lot of fake flash out there.