3 ms·
Mark, could you comment on MSCs vs iPSCs? A Nobel Prize was awarded in 2012 [1] and I'm aware of many labs using these "Yamanaka factors" to reprogram different
by kathrynloving 9y ago
Mark, could you comment on MSCs vs iPSCs? A Nobel Prize was awarded in 2012 [1] and I'm aware of many labs using these "Yamanaka factors" to reprogram differentiated body cells (like skin) into stem cells. And it is possible to move stem cells between people [2]. Right now of course everyone is waiting for additional data on stem cell therapies (and for regulation to catch up [3])... but by the time therapies are approved for stored MSCs, wouldn't people just be creating allogenic iPSC "young stem cells" on-demand? Curious to hear your thoughts!
[1] https://www.nobelprize.org/nobel_prizes/medicine/laureates/2012/press.html https://www.nobelprize.org/nobel_prizes/medicine/laureates/2...
[2] https://www.nature.com/news/japanese-man-is-first-to-receive-reprogrammed-stem-cells-from-another-person-1.21730 https://www.nature.com/news/japanese-man-is-first-to-receive...
[3] https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm573443.htm https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/u...