3 ms·
Contrary to what the article states, elevated levels of lactic acid per say do not cause acidification. In fact, the increase in lactic acid correlates to but i
by Ovah 9y ago
Contrary to what the article states, elevated levels of lactic acid per say do not cause acidification. In fact, the increase in lactic acid correlates to but is not the causation of acidosis.
According to Robergs (2004) [1], it is the hydrolysis of ATP outside of the mitochondria (ATP produced in glycolysis) that increases the concentration of H+ and lowers pH.
Yet, still, if the concentration of lactate increases it's a good indicator of acidosis from oxygen deficiency.
[1]
Biochemistry of exercise-induced metabolic acidosis.
https://www.ncbi.nlm.nih.gov/pubmed/15308499 https://www.ncbi.nlm.nih.gov/pubmed/15308499
Note: During low oxygen levels in tissue, metabolism becomes anaerobic -> lactic acid is produced. Lactic acid <-> lactate + H+.