As with any substance, it can get toxic with larger doses (you can die from to much water for example). From what I remember when I read toxicity studies about

As with any substance, it can get toxic with larger doses (you can die from to much water for example). From what I remember when I read toxicity studies about MDMA about 150mg in around 3 month time is "ok", leaving no damage. Now, that is medical grade MDMA. Buying stuff on the street is a lottery every time and you will NEVER get pure stuff. One of the reasons why substances should be legal and regulated in a different way. Regarding supplements for MDMA, yeah things like 5HTP could help mitigate the damage and speed up the recovery if you take too much.