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Interesting how Meldonium works. When I was doing research on SARMs, GW501516 often came up. It basically works in the opposite way that Meldonium does, increa
by 0x8BADF00D 9y ago
Interesting how Meldonium works.
When I was doing research on SARMs, GW501516 often came up.
It basically works in the opposite way that Meldonium does, increasing cellular metabolic preference for lipids as opposed to glucose. I wonder which metabolic pathway is optimal for weight-loss; probably a combination of the two.
- dnautics 9y agoI hiked up a modest mountain to watch the eclipse and found myself winded after about 1 hour of light (~10-15 degree incline) and my feet were like trudging through molasses for the remaining 4 hours of climb (45+-ish degree incline)... I'm not in terrible shape (I can do 11 pull ups, and maybe about an hour of medium cardio without discomfort at sea level). I wonder if meldonium could be used to combat altitude sickness.
- mahyarm 9y agoI would think twice about it although. GW501516 for example: 'was abandoned in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs'
- dnautics 9y agothat's understandable, since it kicks in fat burning, which is a more oxidative process, there's likely to be more oxidative stress on the cell. Meldronum on the other hand reduces the net oxidation performed by the cell by shifting. Of course, the eye is a very bad medchemist, so take what I say with a grain of salt
- bitL 9y agoViagra is for altitude sickness... Serious(ly)
- atomical 9y agoCheck the studies with obese people and GW501516. It doesn't work. They didn't lose much weight.