Ask HN: Would you accept to work with a lower salary in a startup?

If you had to choose between working in a startup with a lower salary (but better condition such as flexibility, challenges, etc.) or in a huge company, what would you choose? In this post, I kind of act like working in a big company wasn't challenging or flexible. It might not be true for all cases, but it is for the decision I need to take. Let's say it's about 15k-20k lower.