The major spike in the graph occurs in 2012, so its something approved between 2010-2012. "The analysis also showed a greater increase in claims in rural areas

The major spike in the graph occurs in 2012, so its something approved between 2010-2012. "The analysis also showed a greater increase in claims in rural areas than in cities. " It could be some pesticide/herbicide approved in the above time range. Some pesticide residue could be a sensitizing trigger turning immune system into overdrive.