Like anything health related, it really depends on many factors (overall health, genetics, other risk factors) as to weather sitting will have a significant eff

Like anything health related, it really depends on many factors (overall health, genetics, other risk factors) as to weather sitting will have a significant effect on your health. For some, it may never affect them much. But, it won't be a short term thing - you won't know until after many years of sitting. The negative effects of sitting aren't the kinds of things you can reverse.