It's great that Qt works with virtualenv and pip, Wx does too. This is a quite recent phenomenon and to be applauded. Minus sides - Neither of these work wit

It's great that Qt works with virtualenv and pip, Wx does too. This is a quite recent phenomenon and to be applauded. Minus sides - Neither of these work with pypy yet (ideally the bindings would be rewritten using cffi for best benefit). The downloads on these are quite big, but maybe this isn't the end of the world. Gtk still doesn't work with pip like that yet. Pyimgui may be worth a look if you want a small download that works everywhere, though it does look like it's own thing.