5 ms·
It's not a silly question, it's an interesting one to ask. The short answer is: probably not, but maybe!, as some of these tests and assays are sometimes run o
by doctoring 9y ago
It's not a silly question, it's an interesting one to ask.
The short answer is: probably not, but maybe!, as some of these tests and assays are sometimes run on "healthy" people as part of testing and validation. So you might be able to convince some of these labs or companies to "test" you. But my spouse, who is one of the authors of the OP paper, ran into this issue when one of the lab members tested "positive" for a cancer-associated mutation during early-phase development of some of the assays. (They were running the stuff on their own blood.) The team was kind of stumped: the tests at that point were intended for characterizing cancer, with only inklings of ideas that it could be used for screening for cancer in seemingly-healthy people. It highlights the challenge: then what?
The outstanding question in this space is indeed: then what? We're getting to the point where we can detect tumor DNA with extremely high sensitivity. But if you are found to have DNA in your blood that could be from cancer, then what?
Whole-body CT scan? PET scan? MRI? And you find a node, a nodule, a mass... then what? Biopsy it? And then what? Cut it out? Chemotherapy? Watch it?
Each step is fraught with cost and worry and risk and potential morbidity, eg CT scans irradiate you... which can cause cancer.
We have no idea what to do with the information at this point. In fact, in some cases (as mentioned in other threads) even when we KNOW you have a specific cancer, it turns out to be better to watch and wait rather than do anything, because it can be expensive and harmful and risky to go hunting, when the cancer turns out to be slow and predictable. But it took us decades to figure that out, and to figure out which this was the case for.
So I would advise not getting such a test anytime soon, even if you could. There's nothing to do with information at the moment. As for the lab member, they ended up not doing anything about that result.
But it is still a good question, because the only way we begin to find out what to do with this kind of information is to begin collecting it.
- webreac 9y agoIf I am diagnose as early cancer, it could be a good motivation to switch to a more healthy lifestyle: more sleep, less food, ...
- hycaria 9y agoBut if you don't, it's not worth it ? Everyone could benefit from a healthier lifestyle. I have a hard time believing that would be a wake up call for a significant percentage of people (see smokers, obesity, ...).
- intrasight 9y agoI recently discussed this very question with a colleague, and we both agreed that it probably would be a "wake up call". Currently, we really lack quality heath data, and so the loudest pundit or charlatan is who people listen to. And what they mostly present are anecdotes. Having high-fidelity health data about me as an individual and as part of various cohort study groups would allow my doctor to say "This is you now. These are the various future you's if you pursue these different lifestyles".
- deleted 9y ago[deleted]