I was unaware that IgE producing B cells transform to IgG after repeated exposure. My previous understanding was that IgE production was a terminal state and r

I was unaware that IgE producing B cells transform to IgG after repeated exposure. My previous understanding was that IgE production was a terminal state and responded similarly to increased antigen on IgG presenting Bcells. The hygiene hypothesis makes a good bit more sense now, given that transformation. Thanks for clarifying that.