2 ms·
True, but it seems unlikely that CFS could be caused by the mitochondria or intestinal update suddenly screwing up overnight. A neuropsychiatric disorder caused
by cpncrunch 9y ago
True, but it seems unlikely that CFS could be caused by the mitochondria or intestinal update suddenly screwing up overnight. A neuropsychiatric disorder caused by chronic stress seems more plausible, with both the fatigue and depression being generated in the brain itself.
- manmal 9y agoMany people describe that their CFS started right after coming down with a virus, so a malfunctioning immune system seems a cofactor. Impaired T cells have been hypothesized..
- cpncrunch 9y agoIf you look at the research (e.g. http://www.sciencedirect.com/science/article/pii/S0022395696000507 http://www.sciencedirect.com/science/article/pii/S0022395696...) most people report a viral infection and stressful events (more people report stress than virus). Bear in mind that infections are physiologically stressful (http://dx.doi.org/10.1089/vim.2005.18.41 http://dx.doi.org/10.1089/vim.2005.18.41) in that they activate the HPA axis in the same way that a psychological stressor does. >a malfunctioning immune system seems a cofactor. Impaired T cells have been hypothesized.. But there has to be a reason for that suddenly happening. And it doesn't explain patients who didn't have a viral infection at onset, or those who don't have ongoing EBV (or other) infections...