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I think the better summary would be "there will never be a pill against aging that works through altering metabolism, ultimately mimicking calorie restriction".

I think the better summary would be "there will never be a pill against aging that works through altering metabolism, ultimately mimicking calorie restriction". The reason is simple: even calorie restriction is not a solution to aging, so calorie restriction mimic can't be. I think this is obviously correct. I think Reason is neutral about other ways against aging which is not through metabolism.

p1esk 9y ago
There's nothing "obvious" about aging, and we don't even understand how or why calorie restriction works [1]. [1] https://en.wikipedia.org/wiki/Calorie_restriction#Mechanisms https://en.wikipedia.org/wiki/Calorie_restriction#Mechanisms