4 ms·
CFS is in the blood. There are now several different researchers that have reported that there is something in the blood of patients that induces abnormal metab
by nihy 9y ago
CFS is in the blood. There are now several different researchers that have reported that there is something in the blood of patients that induces abnormal metabolism in cells. CFS cells taken out of the patient's blood and into healthy blood are mostly normal. Muscle cells grown in presence of CFS blood show altered metabolism.
Only one group has published their findings here
http://insight.jci.org/articles/view/89376 http://insight.jci.org/articles/view/89376
During this conference Ron Davis showed some of his data on this. CFS cells subjected to salt stress can't keep up with the resulting increased ATP demands: https://www.youtube.com/watch?v=s7bBMXQSmuM&t=25748 https://www.youtube.com/watch?v=s7bBMXQSmuM&t=25748
Another researcher present at the conference also found abnormally low metabolism in T cells of patients.
- nihy 9y agoA better slide from the conference comparing - Healthy plasma and healthy cells - CFS cells in CFS plasma - CFS cells exposed to salt ATP/salt stress - CFS cells exposed to pyruvate/salt stress https://www.youtube.com/watch?v=s7bBMXQSmuMt=25900 https://www.youtube.com/watch?v=s7bBMXQSmuMt=25900 Pyruvate allows the CFS cells to tollerate the stress, suggesting that there is a defect in energy production. Pyruvate is one the fuels used in the Krebs cycle to produce ATP.
- zkms 9y ago> Only one group has published their findings here http://insight.jci.org/articles/view/89376 http://insight.jci.org/articles/view/89376 that is a very interesting paper, ty for linking it here.