Why are all these studies always done so poorly? One way to add another level to test the sweetness mismatch theory would be to try multiple sweeteners. She on

Why are all these studies always done so poorly? One way to add another level to test the sweetness mismatch theory would be to try multiple sweeteners. She only tries sucralose. If others fail, her theory is probably wrong. The article also says there was a higher metabolic response defined as using more calories to process the drinks at the 50-50 level. How does that lead to storing more calories? (I might be misunderstanding this part though). And is the mismatch is worse at the 50-50 level then eating more carbs would be better (get you off that peak) so a full meal would vastly negate the effect?