Since I've not seen it mentioned yet: I use CrashPlan to back up all of my personal systems, both to a home server and to an remote peer. It's a bit RAM heavy,

Since I've not seen it mentioned yet: I use CrashPlan to back up all of my personal systems, both to a home server and to an remote peer. It's a bit RAM heavy, but other than that nicely stays out of the way & does it's job. The killer feature is trivial peer-to-peer connectivity, making off site backups easy. I'm not affiliated with the company -- just a happy customer.